Archive for January, 2008

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Monday, January 28th, 2008

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Rimonabant/Acomplia by Sanofi-Aventis (SNY) was touted as a blockbuster drug in the obviously lucrative market sector of obesity. Diet and exercise have generally been shown to fail and dieting may actually make obesity more difficult to reverse.While bariatric (obesity) surgeries are the fastest growing operations in America, they have generally been reserved for the most overweight, the morbidly obese or those likely to die of obesity. Somewhere in the neighborhood of 30% of the U.S. population could qualify for long-term pharmacological treatment.The recent history of pharmacological treatments has not gone well. The pharmaceutical treatments do cause significant weight loss but side effects have been the rule rather than the exception. First there was Phen-Fen. While effective, cardiologists at Mayo clinic observed and reported that it caused heart valve changes. This report ultimately led to Fen’s (fenfluarmine; dexfenfluramine—Wyeth (WYE)) withdrawal from the market and ensuing litigation.
Xenical (Orlistat; Roche (RHHBY)) came next and was touted by the company as a $>1b blockbuster. The company, apparently unhappy with the pace of sales to patients being seen by obesity experts, went directly to the patient with ads [buy acomplia].Unfortunately for them, the side effects were branded in the American public’s consciousness and prescription rates were disappointing. As a pancreatic lipase inhibitor, it blocks the absorption of dietary fat in the gut. Simply stated, the pizza you ate for lunch goes in the mouth and out of the body as a fatty stool or diarrhea. Gas and stool leakage strategies exist but most patients are immediately disinterested when such a discussion starts with their physician. Acomplia is a novel treatment that blocks the brain’s marijuana or THC receptors. It blocks the MJ munchies and slowly appears to interfere with some of the hedonic or rewarding aspects of eating. Unfortunately, the brain’s own marijuana system is extensive and important. All of its functions are not known but it appears important to memory formation, mood, eating, and pain, to name a few obvious candidates. So, it is was not surprising for researchers to discover that a number of patients treated for obesity developed depression out of the blue. Acomplia is made by the French pharmaceutical giant sanofi-aventis; the generic name of the drug is rimonabant. It has been authorized in the European Union since June 2006, to be used in combination with diet and exercise to help obese and overweight patients lose weight. It was not approved as a smoking cessation agent. Clinical trials showed that it could help patients lose 10 per cent of their body weight [buy acomplia].A warning was issued when it was approved by the EMEA informing doctors not to prescribe it to patients on anti-depressants because of risk of psychiatric side effects, and depression in particular. Information accompanying the drug indicated that doctors should not prescribe it to patients with uncontrolled serious psychiatric conditions such as major depression.
Acomplia diet pill is used as a treatment to aid weight loss. Acomplia diet drug is an oral medication that is used for weight reduction. Acomplia helps in reducing appetite, and thus being effective in weight loss. It also appears to be effective against certain metabolic disorders and associated heart risk factors.

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Acomplia is a trade name of Rimonabant which is an anorectic anti-obesity diet drug. Rimonabant, discovered and developed by French pharmaceutical company Sanofi-Synthelabo, is a new diet drug, to provide relief to the ever growing number of overweight people across the world. The eagerly awaited diet drug acomplia is now in the market and is sold in United Kingdom by world’s third largest pharmaceutical company, Sanofi-Aventis under the name Acomplia. It is anticipated that if the drug gets approved by FDA, it will be sold under name Zimulti in United States.Acomplia has managed to entice overweight community by showing promising results in trials for weight reduction and related metabolic risk factors. Though acomplia has gained popularity mostly as a new diet drug used for effective weight reduction; its efficacy for smokers’ community can be overlooked [buy acomplia].Miracle pill acomplia can do wonders with its dual nature. Acomplia is useful in renouncing the unhealthy habit of smoking along with effective weight control.This site is meant for information related to rimonabant and weight loss only with no intended infringement on the trademark Acomplia.We are not affiliated or endorsed by Sanofi-Aventis. We are neither liable nor responsible for any claim, loss, damage, or lawsuit resulting from any medication use whether purchased through this website or any other website with which this website may associate. We are an independent online advertising medium and have no ability to operate as a pharmacy and hence, have no ability to take orders for prescription drugs and processing of orders. Our site provides referral links to merchants running an Affiliate Program. It is the responsibility of the patient to determine the accuracy and authenticity of the Pharmacy while placing an order with the pharmacy. We make no warranties or representations or any endorsement about the services of the pharmacy listed on the site. Nothing on this site is intended as medical advice [buy acomplia]. The information provided here is for informational purposes only. You are advised to consult your doctor (for medical advice before taking any medication) and a licensed attorney (for any and all legal advice about laws concerning the importation of the drugs to your specific location). Always check with your laws regarding purchasing medication online. We are not responsible to inform anyone of local regulations surrounding these issues. This website is not affiliated by any of the manufacturers of the products offered on this website. We do not provide any medical or legal advice and do not promote or encourage the illegal use of drugs.

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Monday, January 28th, 2008

The weight loss drug Acomplia hasn’t been approved by the FDA, but it’s already drawing attention from the public and scientists.The latest Acomplia headlines appear online in The Cochrane Library.The researchers included graduate student Cintia Curioni, MSc, of Brazil’s University of Rio de Janeiro.They reviewed four studies on Acomplia’s use in more than 6,600 overweight and obese adults.For one or two years, participants either took Acomplia in higher or lower doses (20 milligrams or 5 milligrams daily) or pills containing no medicine (placebo).But they didn’t just pop pills. They also shaved about 600 calories off their daily diet.The studies’ key question: Who lost the most weight?The answer: Participants taking the higher dose of Acomplia.In a year’s time, they lost about 11 more pounds, on average, than those taking the placebo.Dieters taking the lower Acomplia dose lost nearly 3 pounds more in a year than those taking the placebo, on average.Both Acomplia groups trimmed their waists: by an inch and a half with the higher dose and half an inch with the lower dose.People taking the higher dose also showed more improvement in blood pressure and cholesterol than those taking the lower dose or the placebo.But the higher Acomplia dose may have come with more risks.
People taking the higher Acomplia dose were more likely to have adverse effects, “especially of nervous system, psychiatric, and gastrointestinal origin,” Curioni’s team writes.On the one hand, “even modest amounts of weight loss may be potentially beneficial,” write Curioni and colleagues.They note that people taking the higher dose of Acomplia had “modest weight loss of about 5%” of their body weight.But on the other hand, the reviewers call for caution in interpreting the review’s results.They note that about 40% of the participants quit the studies early and none of the studies met the reviewers’ highest standards.Curioni’s team calls for longer, more rigorous studies before making definitive recommendations about the drug’s use in overweight and obese patients.

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Meanwhile, the reviewers say drug-free methods “should remain the cornerstone of obesity therapy” in people who want to lose extra weight.That may sound simple. But diet and exercise are often easier said than done [buy acomplia].If you’re interested in losing weight, consult your doctor to start a healthy weight loss plan.Acomplia, which has been approved in Europe, is made by the drug company Sanofi-Aventis. Sanofi-Aventis has not settled on the drug’s U.S. name pending FDA approval. Sanofi-Aventis is a WebMD sponsor.There are a number of different weight loss pills available. Most of these pills are only available to people that have a doctors prescription, with the exception of the natural herbal treatments.A common weight loss drug is called Acomplia, this works by controlling hunger. Many people have uncontrollable appetites and will eat too much, this drug effectively limits their appetite, and so should prevent overeating. Acomplia is normally [buy cheap acomplia] taken with other drugs, and it works best with some form of exercise and diet regimen.Many companies produce Acomplia pills branded with their own name like Slimona, Obitone or simply it’s generic name Rimonabant.Acomplia is anorectic, it makes your heart rate and blood pressure increase. Because your metabolic rate is increased, your appetite is reduced. The patient should keep a true diary of what they eat so the doctor is able to monitor just what is working. The Acomplia drug should stop any snacking, which makes weight loss possible.Normally the Acomplia drugs are taken either once or twice a day, they can be taken at meal time or on an empty stomach. The pill should be swallowed whole, chewing or crushing the pill can lesson the effectiveness of this drug.If a person who has been prescribed Acomplia misses a dose then it is not the end of the world. If the person does not notice until the time of the next dose, then this dose should be skipped [buy acomplia].Be careful with your dosage when using these diet pills, if you accidentally take an overdose you would suffer from rapid breathing, hallucinations, diarrhea. If you believe you have taken an overdose then it is important to get medical advice as soon as possible.